Cancer genetic regulatory network
Originea cancerului - Cancer genetic network Cancer genetic cancer genetic regulatory network network We plan to further refine our current understanding of the molecular-level processes responsible in this disease in the framework of future projects and with the help of a specialized molecular-biology lab by using various high-throughput technologies not just microarrays to dissect the pathways involved in PDAC and to test these on cell lines and possibly animal models.
Bioinformatic cancer genetic regulatory network of the lung cancer dataset of Bhattacharjee et al. We are therefore using them in conjunction with literature analysis tools for - validating certain transcriptional influences, as well as - emphasizing the various signaling pathways in which these genes operate.
The partial results are very encouraging. For example, for the squamous cell lung carcinoma we have found essentially two groups of differentially expressed genes: - a set of upregulated genes involved e.
Apparently, this cancer subtype seems to be due to a defective re-enactment of normal developmental processes at a wrong time and place. Combined gene expression analysis of whole-tissue and microdissected pancreatic ductal adenocarcinoma identifies genes specifically overexpressed in tumor epithelia. Generalized Clustergrams for Overlapping Biclusters.
Studies in Informatics and Control, Vol. Bry, C. Koch, T. Furche, S. Schaffert, L. Badea, S. Towards a semantic web for bioinformatics.